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An improved deep learning method for predicting DNA-binding proteins based on contextual features in amino acid sequences

As the number of known proteins has expanded, how to accurately identify DNA binding proteins has become a significant biological challenge. At present, various computational methods have been proposed to recognize DNA-binding proteins from only amino acid sequences, such as SVM, DNABP and CNN-RNN....

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Detalles Bibliográficos
Autores principales: Hu, Siquan, Ma, Ruixiong, Wang, Haiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855455/
https://www.ncbi.nlm.nih.gov/pubmed/31725778
http://dx.doi.org/10.1371/journal.pone.0225317