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Chromosome territory formation attenuates the translocation potential of cells

The formation and spatial arrangement of chromosome territories (CTs) in interphase has been posited to influence the outcome and frequency of genomic translocations. This is supported by correlations between the frequency of inter-chromosomal contacts and translocation events in myriad systems. How...

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Detalles Bibliográficos
Autores principales: Rosin, Leah F, Crocker, Olivia, Isenhart, Randi L, Nguyen, Son C, Xu, Zhuxuan, Joyce, Eric F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855801/
https://www.ncbi.nlm.nih.gov/pubmed/31682226
http://dx.doi.org/10.7554/eLife.49553