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Single-cell proteomics reveals changes in expression during hair-cell development

Hearing and balance rely on small sensory hair cells that reside in the inner ear. To explore dynamic changes in the abundant proteins present in differentiating hair cells, we used nanoliter-scale shotgun mass spectrometry of single cells, each ~1 picoliter, from utricles of embryonic day 15 chicke...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Scheibinger, Mirko, Ellwanger, Daniel Christian, Krey, Jocelyn F, Choi, Dongseok, Kelly, Ryan T, Heller, Stefan, Barr-Gillespie, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855842/
https://www.ncbi.nlm.nih.gov/pubmed/31682227
http://dx.doi.org/10.7554/eLife.50777