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5-Aminolevulinic Acid Fluorescence-Guided Resection of (18)F-FET-PET Positive Tumor Beyond Gadolinium Enhancing Tumor Improves Survival in Glioblastoma

BACKGROUND: The value of early postoperative (18)F-FET-PET in patients with glioblastoma (GBM) is unclear. Five-aminolevulinic acid (5-ALA) is used for fluorescence-guided resections in these patients and previous data suggest that fluorescence and (18)F-FET-PET both demarcate larger tumor volumes t...

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Detalles Bibliográficos
Autores principales: Müther, Michael, Koch, Raphael, Weckesser, Matthias, Sporns, Peter, Schwindt, Wolfram, Stummer, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855932/
https://www.ncbi.nlm.nih.gov/pubmed/31215632
http://dx.doi.org/10.1093/neuros/nyz199