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A High-Content Screening Approach to Identify MicroRNAs Against Head and Neck Cancer Cell Survival and EMT in an Inflammatory Microenvironment

Head and neck squamous cell carcinoma (HNSCC) is among the most common cancer types. Metastasis, the main cause of death by cancer, can be promoted by an inflammatory microenvironment, which induces epithelial-mesenchymal transition (EMT) through a NF-κB-mediated stabilization of Snail. Here, we aim...

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Detalles Bibliográficos
Autores principales: Sangiorgi, Bruno, de Souza, Felipe Canto, Mota de Souza Lima, Ildercílio, dos Santos Schiavinato, Josiane Lilian, Corveloni, Amanda Cristina, Thomé, Carolina Hassibe, Araújo Silva, Wilson, Faça, Vitor Marcel, Covas, Dimas Tadeu, Zago, Marco Antônio, Panepucci, Rodrigo Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856008/
https://www.ncbi.nlm.nih.gov/pubmed/31788442
http://dx.doi.org/10.3389/fonc.2019.01100