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Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation

Alzheimer’s disease (AD) pathology is characterized by the aggregation of beta-amyloid (Aβ) and tau in the form of amyloid plaques and neurofibrillary tangles in the brain. It has been found that a synergistic relationship between these two proteins may contribute to their roles in disease progressi...

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Detalles Bibliográficos
Autores principales: Shin, Woo Shik, Di, Jing, Murray, Kevin A., Sun, Chuanqi, Li, Binsen, Bitan, Gal, Jiang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856013/
https://www.ncbi.nlm.nih.gov/pubmed/31787880
http://dx.doi.org/10.3389/fnmol.2019.00268