Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism

Clavulanic acid is a bacterial specialized metabolite, which inhibits certain serine β-lactamases, enzymes that inactivate β-lactam antibiotics to confer resistance. Due to this activity, clavulanic acid is widely used in combination with penicillin and cephalosporin (β-lactam) antibiotics to treat...

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Detalles Bibliográficos
Autores principales: AbuSara, Nader F., Piercey, Brandon M., Moore, Marcus A., Shaikh, Arshad Ali, Nothias, Louis-Félix, Srivastava, Santosh K., Cruz-Morales, Pablo, Dorrestein, Pieter C., Barona-Gómez, Francisco, Tahlan, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856088/
https://www.ncbi.nlm.nih.gov/pubmed/31787949
http://dx.doi.org/10.3389/fmicb.2019.02550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856088/
https://www.ncbi.nlm.nih.gov/pubmed/31787949
http://dx.doi.org/10.3389/fmicb.2019.02550

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