Mebendazole for Differentiation Therapy of Acute Myeloid Leukemia Identified by a Lineage Maturation Index

Accurate assessment of changes in cellular differentiation status in response to drug treatments or genetic perturbations is crucial for understanding tumorigenesis and developing novel therapeutics for human cancer. We have developed a novel computational approach, the Lineage Maturation Index (LMI...

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Detalles Bibliográficos
Autores principales: Li, Yulin, Thomas, Daniel, Deutzmann, Anja, Majeti, Ravindra, Felsher, Dean W., Dill, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856101/
https://www.ncbi.nlm.nih.gov/pubmed/31727951
http://dx.doi.org/10.1038/s41598-019-53290-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856101/
https://www.ncbi.nlm.nih.gov/pubmed/31727951
http://dx.doi.org/10.1038/s41598-019-53290-3

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