Ubiquitylation and endocytosis of the human LAT1/SLC7A5 amino acid transporter

The human L-type amino acid transporter 1 (LAT1), also known as SLC7A5, catalyzes the transport of large neutral amino acids across the plasma membrane. As the main transporter of several essential amino acids, notably leucine, LAT1 plays an important role in mTORC1 activation. Furthermore, it is ov...

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Detalles Bibliográficos
Autores principales: Barthelemy, Céline, André, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856120/
https://www.ncbi.nlm.nih.gov/pubmed/31728037
http://dx.doi.org/10.1038/s41598-019-53065-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856120/
https://www.ncbi.nlm.nih.gov/pubmed/31728037
http://dx.doi.org/10.1038/s41598-019-53065-w

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