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Ubiquitylation and endocytosis of the human LAT1/SLC7A5 amino acid transporter
The human L-type amino acid transporter 1 (LAT1), also known as SLC7A5, catalyzes the transport of large neutral amino acids across the plasma membrane. As the main transporter of several essential amino acids, notably leucine, LAT1 plays an important role in mTORC1 activation. Furthermore, it is ov...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856120/ https://www.ncbi.nlm.nih.gov/pubmed/31728037 http://dx.doi.org/10.1038/s41598-019-53065-w |