Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

Enhanced bone marrow adipogenesis and impaired osteoblastogenesis have been observed in obesity, suggesting that the metabolic microenvironment regulates bone marrow adipocyte and osteoblast progenitor differentiation fate. To determine the molecular mechanisms, we studied two immortalized murine ce...

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Detalles Bibliográficos
Autores principales: Tencerova, Michaela, Rendina-Ruedy, Elizabeth, Neess, Ditte, Færgeman, Nils, Figeac, Florence, Ali, Dalia, Danielsen, Morten, Haakonsson, Anders, Rosen, Clifford J., Kassem, Moustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856123/
https://www.ncbi.nlm.nih.gov/pubmed/31754546
http://dx.doi.org/10.1038/s41413-019-0076-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856123/
https://www.ncbi.nlm.nih.gov/pubmed/31754546
http://dx.doi.org/10.1038/s41413-019-0076-5

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