Engineering a Virus-Like Particle as an Antigenic Platform for a Pfs47-Targeted Malaria Transmission-Blocking Vaccine

We recently characterized Pfs47, a protein expressed on the surface of sexual stages and ookinetes of Plasmodium falciparum, as a malaria transmission-blocking vaccine (TBV) target. Mice immunization induced antibodies that conferred strong transmission-reducing activity (TRA) at a concentration of...

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Detalles Bibliográficos
Autores principales: Yenkoidiok-Douti, Lampouguin, Williams, Adeline E., Canepa, Gaspar E., Molina-Cruz, Alvaro, Barillas-Mury, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856133/
https://www.ncbi.nlm.nih.gov/pubmed/31727945
http://dx.doi.org/10.1038/s41598-019-53208-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856133/
https://www.ncbi.nlm.nih.gov/pubmed/31727945
http://dx.doi.org/10.1038/s41598-019-53208-z

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