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Engineering a Virus-Like Particle as an Antigenic Platform for a Pfs47-Targeted Malaria Transmission-Blocking Vaccine

We recently characterized Pfs47, a protein expressed on the surface of sexual stages and ookinetes of Plasmodium falciparum, as a malaria transmission-blocking vaccine (TBV) target. Mice immunization induced antibodies that conferred strong transmission-reducing activity (TRA) at a concentration of...

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Detalles Bibliográficos
Autores principales:	Yenkoidiok-Douti, Lampouguin, Williams, Adeline E., Canepa, Gaspar E., Molina-Cruz, Alvaro, Barillas-Mury, Carolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856133/ https://www.ncbi.nlm.nih.gov/pubmed/31727945 http://dx.doi.org/10.1038/s41598-019-53208-z

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