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Application of extracellular flux analysis for determining mitochondrial function in mammalian oocytes and early embryos

Mitochondria provide the major source of ATP for mammalian oocyte maturation and early embryo development. Oxygen Consumption Rate (OCR) is an established measure of mitochondrial function. OCR by mammalian oocytes and embryos has generally been restricted to overall uptake and detailed understandin...

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Detalles Bibliográficos
Autores principales: Muller, Bethany, Lewis, Niamh, Adeniyi, Tope, Leese, Henry J., Brison, Daniel R., Sturmey, Roger G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856134/
https://www.ncbi.nlm.nih.gov/pubmed/31727902
http://dx.doi.org/10.1038/s41598-019-53066-9