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Higher Order Architecture of Designer Peptides Forms Bioinspired 10 nm siRNA Delivery System

The higher-order architecture observed in biological systems, like viruses, is very effective in nucleic acid transport. The replications of this system has been attempted with both synthetic and naturally occurring polymers with mixed results. Here we describe a peptide/siRNA quaternary complex tha...

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Detalles Bibliográficos
Autores principales: Gamboa, Alicia, Urfano, Selina F., Hernandez, Katrina, Fraser, Deborah A., Ayalew, Luladey, Slowinska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856157/
https://www.ncbi.nlm.nih.gov/pubmed/31728030
http://dx.doi.org/10.1038/s41598-019-53462-1