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PGC-1β Induces Susceptibility To Acetaminophen-Driven Acute Liver Failure

Acetaminophen (APAP) is a worldwide commonly used painkiller drug. However, high doses of APAP can lead to acute hepatic failure and, in some cases, death. Previous studies indicated that different factors, including life-style and metabolic diseases, could predispose to the risk of APAP-induced liv...

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Detalles Bibliográficos
Autores principales: Piccinin, Elena, Ducheix, Simon, Peres, Claudia, Arconzo, Maria, Vegliante, Maria Carmela, Ferretta, Anna, Bellafante, Elena, Villani, Gaetano, Moschetta, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856160/
https://www.ncbi.nlm.nih.gov/pubmed/31727907
http://dx.doi.org/10.1038/s41598-019-53015-6