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Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function

Synapsin I is a phosphoprotein that coats the cytoplasmic side of synaptic vesicles and regulates their trafficking within nerve terminals. Autoantibodies against Syn I have been described in sera and cerebrospinal fluids of patients with numerous neurological diseases, including limbic encephalitis...

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Detalles Bibliográficos
Autores principales: Rocchi, Anna, Sacchetti, Silvio, De Fusco, Antonio, Giovedi, Silvia, Parisi, Barbara, Cesca, Fabrizia, Höltje, Markus, Ruprecht, Klemens, Ahnert-Hilger, Gudrun, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856194/
https://www.ncbi.nlm.nih.gov/pubmed/31727880
http://dx.doi.org/10.1038/s41419-019-2106-z