Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism

Lipotoxicity is a key player in the pathogenesis of nonalcoholic steatohepatitis (NASH), a progressive subtype of nonalcoholic fatty liver disease (NAFLD). In the present study, we combine histological, transcriptional and lipidomic approaches to dissociate common and specific alterations induced by...

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Detalles Bibliográficos
Autores principales: Montandon, Sophie A., Somm, Emmanuel, Loizides-Mangold, Ursula, de Vito, Claudio, Dibner, Charna, Jornayvaz, François R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856196/
https://www.ncbi.nlm.nih.gov/pubmed/31728041
http://dx.doi.org/10.1038/s41598-019-53346-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856196/
https://www.ncbi.nlm.nih.gov/pubmed/31728041
http://dx.doi.org/10.1038/s41598-019-53346-4

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