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Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism
Lipotoxicity is a key player in the pathogenesis of nonalcoholic steatohepatitis (NASH), a progressive subtype of nonalcoholic fatty liver disease (NAFLD). In the present study, we combine histological, transcriptional and lipidomic approaches to dissociate common and specific alterations induced by...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856196/ https://www.ncbi.nlm.nih.gov/pubmed/31728041 http://dx.doi.org/10.1038/s41598-019-53346-4 |