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Memory-Like Inflammatory Responses of Microglia to Rising Doses of LPS: Key Role of PI3Kγ

Trained immunity and immune tolerance have been identified as long-term response patterns of the innate immune system. The causes of these opposing reactions remain elusive. Here, we report about differential inflammatory responses of microglial cells derived from neonatal mouse brain to increasing...

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Detalles Bibliográficos
Autores principales: Lajqi, Trim, Lang, Guang-Ping, Haas, Fabienne, Williams, David L., Hudalla, Hannes, Bauer, Michael, Groth, Marco, Wetzker, Reinhard, Bauer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856213/
https://www.ncbi.nlm.nih.gov/pubmed/31781091
http://dx.doi.org/10.3389/fimmu.2019.02492