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Upregulation of caveolin-1 and its colocalization with cytokine receptors contributes to beta cell apoptosis

Caveolin-1 (cav-1), the principal structural and signalling protein of caveolae, is implicated in various signalling events, including apoptotic cell death in type 2 diabetes. However, the precise role of beta cells in apoptosis has not been clearly defined. In this study, we investigated the involv...

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Detalles Bibliográficos
Autores principales: Bae, Gong Deuk, Park, Eun-Young, Kim, Kyong, Jang, Se-Eun, Jun, Hee-Sook, Oh, Yoon Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856349/
https://www.ncbi.nlm.nih.gov/pubmed/31728004
http://dx.doi.org/10.1038/s41598-019-53278-z