Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling

Long non-coding RNA THOR (Lnc-THOR) binds to IGF2BP1, essential for its function. We here show that Lnc-THOR is expressed in human glioma tissues and cells. Its expression is extremely low or even undetected in normal brain tissues, as well as in human neuronal cells and astrocytes. We show that Lnc...

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Detalles Bibliográficos
Autores principales: Xue, Jun, Zhong, Shan, Sun, Bo-min, Sun, Qing-Fang, Hu, Liang-Yun, Pan, Si-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856358/
https://www.ncbi.nlm.nih.gov/pubmed/31727877
http://dx.doi.org/10.1038/s41419-019-2093-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856358/
https://www.ncbi.nlm.nih.gov/pubmed/31727877
http://dx.doi.org/10.1038/s41419-019-2093-0

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