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Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling
Long non-coding RNA THOR (Lnc-THOR) binds to IGF2BP1, essential for its function. We here show that Lnc-THOR is expressed in human glioma tissues and cells. Its expression is extremely low or even undetected in normal brain tissues, as well as in human neuronal cells and astrocytes. We show that Lnc...
Autores principales: | Xue, Jun, Zhong, Shan, Sun, Bo-min, Sun, Qing-Fang, Hu, Liang-Yun, Pan, Si-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856358/ https://www.ncbi.nlm.nih.gov/pubmed/31727877 http://dx.doi.org/10.1038/s41419-019-2093-0 |
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