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CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen specific CD8(+) T cell responses by upregulating MHC-I expression

Evasion of the host immune responses is critical for both persistent human papillomavirus (HPV) infection and associated cancer progression. We have previously shown that expression of the homeostatic chemokine CXCL14 is significantly downregulated by the HPV oncoprotein E7 during cancer progression...

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Detalles Bibliográficos
Autores principales: Westrich, Joseph A., Vermeer, Daniel W., Silva, Alexa, Bonney, Stephanie, Berger, Jennifer N., Cicchini, Louis, Greer, Robert O., Song, John I., Raben, David, Slansky, Jill E., Lee, John H., Spanos, William C., Pyeon, Dohun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856418/
https://www.ncbi.nlm.nih.gov/pubmed/31417179
http://dx.doi.org/10.1038/s41388-019-0911-6