Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity

At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA or DNA, respectively. Despite the structural and functional similarities between these receptors, their contribution to autoimmune diseases such as systemic lupus erythematosus (SLE) can be quite diffe...

Descripción completa

Detalles Bibliográficos
Autores principales: Majer, Olivia, Liu, Bo, Kreuk, Lieselotte SM, Krogan, Nevan, Barton, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856441/
https://www.ncbi.nlm.nih.gov/pubmed/31546246
http://dx.doi.org/10.1038/s41586-019-1612-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856441/
https://www.ncbi.nlm.nih.gov/pubmed/31546246
http://dx.doi.org/10.1038/s41586-019-1612-6

Ejemplares similares