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Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity
At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA or DNA, respectively. Despite the structural and functional similarities between these receptors, their contribution to autoimmune diseases such as systemic lupus erythematosus (SLE) can be quite diffe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856441/ https://www.ncbi.nlm.nih.gov/pubmed/31546246 http://dx.doi.org/10.1038/s41586-019-1612-6 |