Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis

BACKGROUND AND OBJECTIVE: Sarilumab binds to the interleukin-6 receptor with high affinity, inhibiting cis and trans signaling by interleukin-6. Sarilumab has demonstrated efficacy and safety in patients with rheumatoid arthritis. The objective of this study was to develop a population-pharmacokinet...

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Detalles Bibliográficos
Autores principales: Xu, Christine, Su, Yaming, Paccaly, Anne, Kanamaluru, Vanaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856490/
https://www.ncbi.nlm.nih.gov/pubmed/31055792
http://dx.doi.org/10.1007/s40262-019-00765-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856490/
https://www.ncbi.nlm.nih.gov/pubmed/31055792
http://dx.doi.org/10.1007/s40262-019-00765-1

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