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Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins

CASK-interactive proteins, Caskin1 and Caskin2, are multidomain neuronal scaffold proteins. Recent data from Caskin1 knockout animals indicated only a mild role of Caskin1 in anxiety and pain perception. In this work, we show that deletion of both Caskins leads to severe deficits in novelty recognit...

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Detalles Bibliográficos
Autores principales: Bencsik, Norbert, Pusztai, Szilvia, Borbély, Sándor, Fekete, Anna, Dülk, Metta, Kis, Viktor, Pesti, Szabolcs, Vas, Virág, Szűcs, Attila, Buday, László, Schlett, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856520/
https://www.ncbi.nlm.nih.gov/pubmed/31727973
http://dx.doi.org/10.1038/s41598-019-53317-9