Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers

Genome-wide association studies (GWAS) have identified associations between thousands of common genetic variants and human traits. However, common variants usually explain a limited fraction of the heritability of a trait. A powerful resource for identifying trait-associated variants is whole genome...

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Detalles Bibliográficos
Autores principales: Höglund, Julia, Rafati, Nima, Rask-Andersen, Mathias, Enroth, Stefan, Karlsson, Torgny, Ek, Weronica E., Johansson, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856527/
https://www.ncbi.nlm.nih.gov/pubmed/31727947
http://dx.doi.org/10.1038/s41598-019-53111-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856527/
https://www.ncbi.nlm.nih.gov/pubmed/31727947
http://dx.doi.org/10.1038/s41598-019-53111-7

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