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p38-Mitogen Activated Kinases Mediate a Developmental Regulatory Response to Amino Acid Depletion and Associated Oxidative Stress in Mouse Blastocyst Embryos

Maternal starvation coincident with preimplantation development has profound consequences for placental-fetal development, with various identified pathologies persisting/manifest in adulthood; the ‘Developmental Origin of Health and Disease’ (DOHaD) hypothesis/model. Despite evidence describing DOHa...

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Detalles Bibliográficos
Autores principales: Bora, Pablo, Thamodaran, Vasanth, Šušor, Andrej, Bruce, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856562/
https://www.ncbi.nlm.nih.gov/pubmed/31788473
http://dx.doi.org/10.3389/fcell.2019.00276