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Dihydroartemisinin Induces Endothelial Cell Autophagy through Suppression of the Akt/mTOR Pathway

Aims: Dihydroartemisinin (DHA), a derivative of artemisinin, suppresses angiogenesis by regulating endothelial cell phenotypes. In this study, we investigated the effect of DHA on endothelial cell autophagy and the underlying mechanisms. Methods: Human umbilical vein endothelial cells (HUVECs) were...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Ren, Yanjun, Hou, Yinglong, Zhang, Caiqing, Wang, Bei, Li, Xiaorui, Sun, Rong, Liu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856569/
https://www.ncbi.nlm.nih.gov/pubmed/31762815
http://dx.doi.org/10.7150/jca.33704