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Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin

Background and Aim: Human SLFN11 gene encodes a protein with structural similarity to RNA helicases, which was reported to sensitize cancer cells to DNA-damaging agents. This study explored the epigenetic regulation and mechanism of SLFN11 in human gastric cancer. Methods: Eight human gastric cancer...

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Detalles Bibliográficos
Autores principales: Peng, Yaojun, Wang, Li, Wu, Liangliang, Zhang, Ling, Nie, Guangjun, Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856579/
https://www.ncbi.nlm.nih.gov/pubmed/31762822
http://dx.doi.org/10.7150/jca.32511