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Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

The mitochondrial membrane potential (ΔΨ(m)) is the main driver of oxidative phosphorylation (OXPHOS). The inner mitochondrial membrane (IMM), consisting of cristae and inner boundary membranes (IBM), is considered to carry a uniform ΔΨ(m). However, sequestration of OXPHOS components in cristae memb...

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Detalles Bibliográficos
Autores principales: Wolf, Dane M, Segawa, Mayuko, Kondadi, Arun Kumar, Anand, Ruchika, Bailey, Sean T, Reichert, Andreas S, van der Bliek, Alexander M, Shackelford, David B, Liesa, Marc, Shirihai, Orian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856616/
https://www.ncbi.nlm.nih.gov/pubmed/31609012
http://dx.doi.org/10.15252/embj.2018101056