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TRIM8 Blunts the Pro-proliferative Action of ΔNp63α in a p53 Wild-Type Background

The p53 gene family network plays a pivotal role in the control of many biological processes and therefore the right balance between the pro-apoptotic and pro-survival isoforms is key to maintain cellular homeostasis. The stability of the p53 tumor suppressor protein and that of oncogenic ΔNp63α, is...

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Detalles Bibliográficos
Autores principales: Caratozzolo, Mariano Francesco, Marzano, Flaviana, Abbrescia, Daniela Isabel, Mastropasqua, Francesca, Petruzzella, Vittoria, Calabrò, Viola, Pesole, Graziano, Sbisà, Elisabetta, Guerrini, Luisa, Tullo, Apollonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856647/
https://www.ncbi.nlm.nih.gov/pubmed/31781486
http://dx.doi.org/10.3389/fonc.2019.01154