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Tamoxifen Blocks the Development of Motivational Features of an Addiction-Like Phenotype in Female Rats

Women become addicted sooner after initiating cocaine use as compared to men. Preclinical studies reveal a similar vulnerability in females, with findings from ovariectomized rats suggesting that estradiol mediates the enhanced vulnerability. However, since ovariectomy depletes not only estradiol, b...

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Detalles Bibliográficos
Autores principales: Bakhti-Suroosh, Anousheh, Nesil, Tanseli, Lynch, Wendy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856674/
https://www.ncbi.nlm.nih.gov/pubmed/31780909
http://dx.doi.org/10.3389/fnbeh.2019.00253