The Architecture of Talin1 Reveals an Autoinhibition Mechanism

Focal adhesions (FAs) are protein machineries essential for cell adhesion, migration, and differentiation. Talin is an integrin-activating and tension-sensing FA component directly connecting integrins in the plasma membrane with the actomyosin cytoskeleton. To understand how talin function is regul...

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Detalles Bibliográficos
Autores principales: Dedden, Dirk, Schumacher, Stephanie, Kelley, Charlotte F., Zacharias, Martin, Biertümpfel, Christian, Fässler, Reinhard, Mizuno, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856716/
https://www.ncbi.nlm.nih.gov/pubmed/31539492
http://dx.doi.org/10.1016/j.cell.2019.08.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856716/
https://www.ncbi.nlm.nih.gov/pubmed/31539492
http://dx.doi.org/10.1016/j.cell.2019.08.034

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