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The Architecture of Talin1 Reveals an Autoinhibition Mechanism

Focal adhesions (FAs) are protein machineries essential for cell adhesion, migration, and differentiation. Talin is an integrin-activating and tension-sensing FA component directly connecting integrins in the plasma membrane with the actomyosin cytoskeleton. To understand how talin function is regul...

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Detalles Bibliográficos
Autores principales:	Dedden, Dirk, Schumacher, Stephanie, Kelley, Charlotte F., Zacharias, Martin, Biertümpfel, Christian, Fässler, Reinhard, Mizuno, Naoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856716/ https://www.ncbi.nlm.nih.gov/pubmed/31539492 http://dx.doi.org/10.1016/j.cell.2019.08.034

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