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A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2

Pluripotent embryonic stem cells (ESCs) constitute an essential cellular niche sustained by epigenomic and transcriptional regulation. Any role of post-transcriptional processes remains less explored. Here, we identify a link between nuclear RNA levels, regulated by the poly(A) RNA exosome targeting...

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Detalles Bibliográficos
Autores principales: Garland, William, Comet, Itys, Wu, Mengjun, Radzisheuskaya, Aliaksandra, Rib, Leonor, Vitting-Seerup, Kristoffer, Lloret-Llinares, Marta, Sandelin, Albin, Helin, Kristian, Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856724/
https://www.ncbi.nlm.nih.gov/pubmed/31722198
http://dx.doi.org/10.1016/j.celrep.2019.10.011