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Bayesian Estimation of Three-Dimensional Chromosomal Structure from Single-Cell Hi-C Data
The problem of three-dimensional (3D) chromosome structure inference from Hi-C data sets is important and challenging. While bulk Hi-C data sets contain contact information derived from millions of cells and can capture major structural features shared by the majority of cells in the sample, they do...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856950/ https://www.ncbi.nlm.nih.gov/pubmed/31211598 http://dx.doi.org/10.1089/cmb.2019.0100 |