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Label-Free Detection of Post-translational Modifications with a Nanopore

[Image: see text] Post-translational modifications (PTMs) of proteins play key roles in cellular processes. Hence, PTM identification is crucial for elucidating the mechanism of complex cellular processes and disease. Here we present a method for PTM detection at the single-molecule level using FraC...

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Detalles Bibliográficos
Autores principales: Restrepo-Pérez, Laura, Wong, Chun Heung, Maglia, Giovanni, Dekker, Cees, Joo, Chirlmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856961/
https://www.ncbi.nlm.nih.gov/pubmed/31602979
http://dx.doi.org/10.1021/acs.nanolett.9b03134