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p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization

High morbidity and mortality are associated with acute liver injury (ALI) for which no effective targeted drugs or pharmacotherapies are available. Discovery of potential therapeutic targets as well as inhibitors that can alleviate ALI is imperative. As excessive inflammatory cytokines released by m...

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Detalles Bibliográficos
Autores principales: Peng, Jinjin, Li, Jiacheng, Huang, Jing, Xu, Pan, Huang, Heming, Liu, Yanjun, Yu, Liang, Yang, Yaxi, Zhou, Bing, Jiang, Hualiang, Chen, Kaixian, Dang, Yongjun, Zhang, Yuanyuan, Luo, Cheng, Li, Guangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857059/
https://www.ncbi.nlm.nih.gov/pubmed/31754401
http://dx.doi.org/10.7150/thno.30707