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Bromodomain and Extraterminal Proteins as Novel Epigenetic Targets for Renal Diseases
Epigenetic mechanisms, especially DNA methylation and histone modifications, are dynamic processes that regulate the gene expression transcriptional program in normal and diseased states. The bromodomain and extraterminal (BET) protein family (BRD2, BRD3, BRD4, and BRDT) are epigenetic readers that,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857099/ https://www.ncbi.nlm.nih.gov/pubmed/31780938 http://dx.doi.org/10.3389/fphar.2019.01315 |