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Bromodomain and Extraterminal Proteins as Novel Epigenetic Targets for Renal Diseases

Epigenetic mechanisms, especially DNA methylation and histone modifications, are dynamic processes that regulate the gene expression transcriptional program in normal and diseased states. The bromodomain and extraterminal (BET) protein family (BRD2, BRD3, BRD4, and BRDT) are epigenetic readers that,...

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Detalles Bibliográficos
Autores principales: Morgado-Pascual, Jose Luis, Rayego-Mateos, Sandra, Tejedor, Lucia, Suarez-Alvarez, Beatriz, Ruiz-Ortega, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857099/
https://www.ncbi.nlm.nih.gov/pubmed/31780938
http://dx.doi.org/10.3389/fphar.2019.01315