Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing

Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds de novo. Therefore, the uptake of polyamines from the extracellular medium is...

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Detalles Bibliográficos
Autores principales: Reigada, Chantal, Sayé, Melisa, Phanstiel, Otto, Valera-Vera, Edward, Miranda, Mariana R., Pereira, Claudio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857147/
https://www.ncbi.nlm.nih.gov/pubmed/31781568
http://dx.doi.org/10.3389/fmed.2019.00256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857147/
https://www.ncbi.nlm.nih.gov/pubmed/31781568
http://dx.doi.org/10.3389/fmed.2019.00256

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