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FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c

BACKGROUND: Excessive intrahepatic lipid accumulation is the major characteristic of nonalcoholic fatty liver disease (NAFLD). We sought to identify the mechanisms involved in hepatic triglyceride (TG) homeostasis. Forkhead box class O (FoxO) transcription factors have been shown to play an importan...

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Detalles Bibliográficos
Autores principales: Wang, Liu, Zhu, Xiaopeng, Sun, Xiaoyang, Yang, Xinyu, Chang, Xinxia, Xia, Mingfeng, Lu, Yan, Xia, Pu, Yan, Hongmei, Bian, Hua, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857156/
https://www.ncbi.nlm.nih.gov/pubmed/31729980
http://dx.doi.org/10.1186/s12944-019-1132-2