Haplotype Analysis of the First A4V-SOD1 Spanish Family: Two Separate Founders or a Single Common Founder?

Despite the genetic heterogeneity reported in familial amyotrophic lateral sclerosis (ALS) (fALS), Cu/Zn superoxide-dismutase (SOD1) gene mutations are the second most common cause of the disease, accounting for around 20% of all families (ALS1) and isolated sporadic cases (sALS). At least 186 diffe...

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Detalles Bibliográficos
Autores principales: Garcia, Cecilia, Vidal-Taboada, Jose Manuel, Syriani, Enrique, Salvado, Maria, Morales, Miguel, Gamez, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857184/
https://www.ncbi.nlm.nih.gov/pubmed/31781168
http://dx.doi.org/10.3389/fgene.2019.01109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857184/
https://www.ncbi.nlm.nih.gov/pubmed/31781168
http://dx.doi.org/10.3389/fgene.2019.01109

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