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Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations?

OBJECTIVES: To demonstrate how phenotypic cell viability data can provide insight into antimycobacterial effects for the isoniazid/rifampicin treatment backbone. METHODS: Data from a Mycobacterium komossense hollow-fibre infection model comprising a growth control group, rifampicin at three differen...

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Detalles Bibliográficos
Autores principales: Kloprogge, Frank, Hammond, Robert, Copas, Andrew, Gillespie, Stephen H, Della Pasqua, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857198/
https://www.ncbi.nlm.nih.gov/pubmed/31504558
http://dx.doi.org/10.1093/jac/dkz369