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Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer

BACKGROUND: Elucidation of regulatory networks, including identification of regulatory mechanisms specific to a given biological context, is a key aim in systems biology. This has motivated the move from co-expression to differential co-expression analysis and numerous methods have been developed su...

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Detalles Bibliográficos
Autores principales: Bhuva, Dharmesh D., Cursons, Joseph, Smyth, Gordon K., Davis, Melissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857226/
https://www.ncbi.nlm.nih.gov/pubmed/31727119
http://dx.doi.org/10.1186/s13059-019-1851-8