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Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer
BACKGROUND: Elucidation of regulatory networks, including identification of regulatory mechanisms specific to a given biological context, is a key aim in systems biology. This has motivated the move from co-expression to differential co-expression analysis and numerous methods have been developed su...
Autores principales: | Bhuva, Dharmesh D., Cursons, Joseph, Smyth, Gordon K., Davis, Melissa J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857226/ https://www.ncbi.nlm.nih.gov/pubmed/31727119 http://dx.doi.org/10.1186/s13059-019-1851-8 |
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