Cargando…

Adjacency-constrained hierarchical clustering of a band similarity matrix with application to genomics

BACKGROUND: Genomic data analyses such as Genome-Wide Association Studies (GWAS) or Hi-C studies are often faced with the problem of partitioning chromosomes into successive regions based on a similarity matrix of high-resolution, locus-level measurements. An intuitive way of doing this is to perfor...

Descripción completa

Detalles Bibliográficos
Autores principales: Ambroise, Christophe, Dehman, Alia, Neuvial, Pierre, Rigaill, Guillem, Vialaneix, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857244/
https://www.ncbi.nlm.nih.gov/pubmed/31807137
http://dx.doi.org/10.1186/s13015-019-0157-4