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Adjacency-constrained hierarchical clustering of a band similarity matrix with application to genomics
BACKGROUND: Genomic data analyses such as Genome-Wide Association Studies (GWAS) or Hi-C studies are often faced with the problem of partitioning chromosomes into successive regions based on a similarity matrix of high-resolution, locus-level measurements. An intuitive way of doing this is to perfor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857244/ https://www.ncbi.nlm.nih.gov/pubmed/31807137 http://dx.doi.org/10.1186/s13015-019-0157-4 |