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Cellular source of hypothalamic macrophage accumulation in diet-induced obesity

BACKGROUND: Obese mice on a high-fat diet (HFD) display signs of inflammation in the hypothalamic arcuate nucleus (ARC), a critical area for controlling systemic energy metabolism. This has been suggested as a key mechanism of obesity-associated hypothalamic dysfunction. We reported earlier that bon...

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Detalles Bibliográficos
Autores principales: Lee, Chan Hee, Shin, Sung Hoon, Kang, Gil Myoung, Kim, Seongjun, Kim, Jiye, Yu, Rina, Kim, Min-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857282/
https://www.ncbi.nlm.nih.gov/pubmed/31727092
http://dx.doi.org/10.1186/s12974-019-1607-0